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Specifications
- Conjugation:Unconjugated
- Size:1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:CPP|Cell penetrating Peptide
- Protein/Peptide Name:Pep-1-Cysteamine
- Purity:95%
- Molecular Weight:2950.3 Da
- Sequence:Ac-KETWWETWWTEWSQPKKKRKV-cysteamine
- Cat. No.:103007-778
- Supplier no.:AS-63849
Specifications
About this item
Pep-1 is one of the synthetic cell-penetrating peptides (CPPs), which has been successfully used to deliver a variety of proteins and other biopharmaceutical macromolecules into cells in a non-disruptive way. It is a CPP with primary amphipathicity (i.e amphipathicity resulting from the amino acid sequence itself, not from the folding structure) that comprises a tryptophan-rich so-called ‘hydrophobic’ domain, a hydrophilic domain derived from an NLS (nuclear localization signal) of SV40 (simian virus 40) large T-antigen, and a spacer between them. A cysteamine group is present at the C-terminus. The presence of cysteamine group in C terminal seems to play a crucial role in the delivery efficiency of cargoes into cells.
Sequence:Ac-KETWWETWWTEWSQPKKKRKV-cysteamine
MW:2950.3 Da
% peak area by HPLC:95
Storage condition:-20° C