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- Conjugation:Biotin
- Size:1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:SRC-1 Peptide|steroid receptor Peptide
- Protein/Peptide Name:Steroid Receptor Coactivator-1
- Purity:95%
- Molecular Weight:3026.5 Da
- Sequence:Biotin-CPSSHSSLTERHKILHRLLQEGSPS
- Cat. No.:103007-220
- Supplier no.:AS-62152
This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminal biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain.
Sequence:Biotin-CPSSHSSLTERHKILHRLLQEGSPS
MW:3026.5 Da
% peak area by HPLC:95
Storage condition:-20° C