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Specifications
- Conjugation:Unconjugated
- Size:1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:Lyp-1 Peptide
- Protein/Peptide Name:LyP-1, Peptide 1
- Purity:95%
- Molecular Weight:992.2 Da
- Sequence:CGNKRTRGC (S-S Bonded)
- Cat. No.:103007-222
- Supplier no.:AS-62169
Specifications
About this item
LyP-1 recognizes lymphatics and tumor cells in certain tumors, but not lymphatics in normal tissues. Screening on breast carcinoma xenografts shows positive to cyclic 9-amino-acid peptide, LyP-1. The LyP-1 also recognizes an osteosarcoma xenograft, and spontaneous prostate and breast cancers in transgenic mice. LyP-1 peptide is detected in tumor structures that are positive for several lymphatic endothelial markers and negative for blood vessel markers. LyP-1 accumulates in the nuclei of the putative lymphatic cells, and in the nuclei of tumor cells.
Sequence:CGNKRTRGC (S-S Bonded)
MW:992.2 Da
% peak area by HPLC:95
Storage condition:-20° C