Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Conjugation:QXL™ 570-TAMRA
- Size:0.1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:MMP Substrate I|MMP FRET|Matrix Metalloproteinase substrate I
- Protein/Peptide Name:580 MMP FRET Substrate I
- Purity:95%
- Molecular Weight:1768 Da
- Sequence:QXL™ 570-KPLA-Nva-Dap(5-TAMRA)-AR-NH2
- Cat. No.:103005-950
- Supplier no.:AS-60585-01
Specifications
About this item
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
With the higher emission wavelength, this substrate is ideal for use in experiments where the test compounds might have strong autofluorescence at shorter wavelength, Abs/Em = 547/574 nm.
Sequence:QXL™ 570-KPLA-Nva-Dap(5-TAMRA)-AR-NH2
MW:1768 Da
% peak area by HPLC:95
Storage condition:-20° C