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- Conjugation:QXL™ 520-FAM
- Size:0.1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:MMP FRET|MMP Substrate III|Matrix Metalloproteinase substrate III
- Protein/Peptide Name:520 MMP FRET Substrate III
- Purity:95%
- Molecular Weight:1743.8 Da
- Sequence:QXL™ 520-PLGC(Me)HAr-K(5-FAM)-NH2
- Cat. No.:103003-242
- Supplier no.:AS-60570-01
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 8, 9, 12, 13 and 14 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PLGC(Me)HAr-K(5-FAM)-NH2
MW:1743.8 Da
% peak area by HPLC:95
Storage condition:-20° C