This peptide is angiontensin I (Ang I) with valine and isoleucine universally labeled with 13C and N. Ang I is a precursor to Ang II, which has been implicated in cardiovascular functions, cell proliferation, fibrosis, and apoptosis. The 10-mer Ang I peptide is converted to Ang II through the cleavage of the Phe8-His9 bond of Ang I by angiotensin-converting enzyme (ACE) or human chymase.
- Sequence: DR-V*-Y-I*-HPFHL [Val* = Val(U-13C5,15N); Ile* = Ile(U-13C6,15N)]
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- Conjugation:Unconjugated
- Species:Human
- Storage Conditions:–20 °C
- Protein Synonyms:Ang I 13C Ang I 15N|13C/15N Ang I|Angiotensin I isotope labeled|Ang I isotope labeled
- Protein/Peptide Name:Ang I isotope labeled
- Purity:95%
- Molecular Weight:1309.5 Da
- Sequence:DR-V*-Y-I*-HPFHL [Val* = Val(U-13C5,15N); Ile* = Ile(U-13C6,15N)]