EndoClear™ Human Recombinant alpha-Synuclein (from E. coli)
About this item
Full-length Recombinant human alpha-synuclein (GenBank Accession # NP_000336) was expressed in E. coli., and purified from bacterial lysate using proprietary method. Endotoxin was further removed by proprietary technique.
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.
The human α-synuclein recombinant proteins from AnaSpec are offered with low endotoxin levels of <0.1 EU per μg protein labeled as EndoClear™ products.
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- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
Full-length Recombinant human alpha-synuclein (GenBank Accession # NP_000336) was expressed in E. coli., and purified from bacterial lysate using proprietary method. Endotoxin was further removed by proprietary technique.
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.
The human α-synuclein recombinant proteins from AnaSpec are offered with low endotoxin levels of <0.1 EU per μg protein labeled as EndoClear™ products.
Documents
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 103001-642
- 103001-646
- 103001-644
- Protein/Peptide Name:
- alpha-Synuclein
- alpha-Synuclein
- alpha-Synuclein
- Protein Synonyms:
- Synuclein Protein|SNCA|low endotoxin synuclein|alpha-Synuclein|low endotoxin alpha-Synuclein|Human alpha - Synuclein|alpha - Synuclein
- Protein/Peptide Type:
- Recombinant
- Recombinant
- Recombinant
- Species:
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- NP_000336
- NP_000336
- NP_000336
- Endotoxin Level:
- Low
- Low
- Low
- Endotoxin Content:
- <0.1EU/µg protein
- <0.1EU/µg protein
- <0.1EU/µg protein
- Purity:
- > 95% as determined by SDS-PAGE
- > 95% as determined by SDS-PAGE
- > 95% as determined by SDS-PAGE
- Molecular Weight:
- 14.5 kDa
- 14.5 kDa
- 14.5 kDa
- Storage Conditions:
- Store at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.
- Store at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.
- Store at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.
Specifications
Product Family Options
Product Information
- SizeAvailabilityPrice
- Supplier Number: AS-55555-100Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:Marketsource
More
Specifications
Cat. No.103001-642Protein/Peptide Namealpha-SynucleinProtein SynonymsSynuclein Protein|SNCA|low endotoxin synuclein|alpha-Synuclein|low endotoxin alpha-Synuclein|Human alpha - Synuclein|alpha - SynucleinProtein/Peptide TypeRecombinantSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDNP_000336Endotoxin LevelLowEndotoxin Content<0.1EU/µg proteinPurity> 95% as determined by SDS-PAGEMolecular Weight14.5 kDaStorage ConditionsStore at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.Marketsource - Supplier Number: AS-55555-500Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:Marketsource
More
Specifications
Cat. No.103001-646Protein/Peptide Namealpha-SynucleinProtein SynonymsProtein/Peptide TypeRecombinantSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDNP_000336Endotoxin LevelLowEndotoxin Content<0.1EU/µg proteinPurity> 95% as determined by SDS-PAGEMolecular Weight14.5 kDaStorage ConditionsStore at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.Marketsource - Supplier Number: AS-55555-1000Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:Marketsource
More
Specifications
Cat. No.103001-644Protein/Peptide Namealpha-SynucleinProtein SynonymsProtein/Peptide TypeRecombinantSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDNP_000336Endotoxin LevelLowEndotoxin Content<0.1EU/µg proteinPurity> 95% as determined by SDS-PAGEMolecular Weight14.5 kDaStorage ConditionsStore at 2-4 °C for immediate use within 1-2 weeks or at –80 °C for up to 12 months.Marketsource
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