Human Recombinant BD-3 (from E. coli)

About this item

Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity. BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.

High quality
Low endotoxin
Affordable

Caution: For research use only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
–20 °C
Endotoxin Content:
Endotoxin LAL (EU/µg) ≤0.1
Biological Activity:
Bioactivity: No biological activity data is available at this time
Gene ID:
P81534
Reconstitution Instructions:
Sterile 10 mM acetic acid at 0.1 mg/ml
Endotoxin-free:
N
Carrier-Free:
Y
Protease-free:
N
Animal-Free:
N
Protein Synonyms:
DEFB-3
Protein/Peptide Name:
BD-3
Purity:
≥95%
Molecular Weight:
5.2 kDa
Sequence:
GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
Endotoxin Level:
Low
Formulation:
0.1% Trifluoroacetic acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping Temperature:
RT