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Specifications
- Conjugation:Unconjugated
- Source:E. coli
- Size:50 µg
- Storage Conditions:–80 °C
- Form:Liquid
- Shipping Conditions:–80 °C, dry ice
- Enzyme Name:NAD Synthetase
- Enzyme Activity:~0.1 U/mg protein. (Ammonium or glutamine as nitrogen source). One unit is defined as the amount of enzyme that synthesizes 1µmol NAD per min.
- Purity:98%
- Molecular Weight:~75.0 kDa
- Concentration:0.5 mg/ml (Lot specific)
- Formulation:In 20 mM TRIS-HCl, pH 7.8.
- Cat. No.:102980-452
- Supplier no.:AG40T0108C050
Specifications
About this item
NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways
- UniProt link P0A5L6: NAD Synthetase (M. tuberculosis)
Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate