Human Recombinant CD134 (from CHO cells)
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Product Details & Documents
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4+ T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.
Specifications
Specifications
- Size:50 µg
- Storage Conditions:–20 °C
- Endotoxin Level:Low
- Purity:98%
- Endotoxin Content:<0.06EU/µg
- Source:CHO cells
- Cat. No.:102981-480
- Shipping Temperature:-20 °C, Blue Ice
- Biological Activity:Measured by its binding ability in a functional ELISA.
- Protein/Peptide Type:Recombinant
- Gene ID:NP_003318.1
- Formulation:Lyophilized from 0.2µm-filtered solution in PBS.
- Protein Synonyms:TXGP1L|ACT35|Tumor Necrosis Factor Receptor Superfamily Member 4|OX40|TNFRSF4
- Protein/Peptide Name:CD134
- Conjugation:Unconjugated
- Species:Human
Specifications
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