Human Recombinant POP (from E. coli)
About this item
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.
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- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
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Product Details & Documents
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 102980-212
- 102980-214
- Protein/Peptide Name:
- POP
- POP
- Protein Synonyms:
- PYC1|Pyrin Domain-containing Protein 1|Pyrin-only Protein 1|PAAD-only Protein 1
- PYC1|Pyrin Domain-containing Protein 1|Pyrin-only Protein 1|PAAD-only Protein 1
- Protein/Peptide Type:
- Recombinant
- Recombinant
- Species:
- Human
- Human
- Source:
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Gene ID:
- Q8WXC3
- Q8WXC3
- Purity:
- 95%
- 95%
- Concentration:
- 0.1mg/ml after reconstitution.
- 0.1mg/ml after reconstitution.
- Formulation:
- Lyophilized. Contains PBS.
- Lyophilized. Contains PBS.
- Molecular Weight:
- ~38 kDa
- ~38 kDa
- Storage Conditions:
- –20 °C
- –20 °C
- Shipping Temperature:
- -20 °C, Blue Ice
- -20 °C, Blue Ice
Specifications
Product Family Options
Product Information
- SizeAvailabilityPrice
- Supplier Number: AG-40B-0123-C010Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:Marketsource
More
Specifications
Cat. No.102980-212Protein/Peptide NamePOPProtein SynonymsPYC1|Pyrin Domain-containing Protein 1|Pyrin-only Protein 1|PAAD-only Protein 1Protein/Peptide TypeRecombinantSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ8WXC3Purity95%Concentration0.1mg/ml after reconstitution.FormulationLyophilized. Contains PBS.Molecular Weight~38 kDaStorage Conditions–20 °CShipping Temperature-20 °C, Blue IceMarketsource - Supplier Number: AG-40B-0123-3010Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:Marketsource
More
Specifications
Cat. No.102980-214Protein/Peptide NamePOPProtein SynonymsPYC1|Pyrin Domain-containing Protein 1|Pyrin-only Protein 1|PAAD-only Protein 1Protein/Peptide TypeRecombinantSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ8WXC3Purity95%Concentration0.1mg/ml after reconstitution.FormulationLyophilized. Contains PBS.Molecular Weight~38 kDaStorage Conditions–20 °CShipping Temperature-20 °C, Blue IceMarketsource
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