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- Antibody Type:Primary
- Antigen Symbol:CD40L
- Clonality:Monoclonal
- Clone:24-31
- ELISA:Yes
- Flow Cytometry:Yes
- Isotype:IgG1
- Reactivity:Primates,Human
- Western Blot:Yes
- Size:120 tests
- Form:liquid
- Storage Temperature:+4°C
- Shipping Temperature:-20° C
- Immunogen:Human sgp39 fusion protein.
- Cat. No.:102513-030
- Supplier no.:ANC353050
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.
Type: Primary
Antigen: CD40L
Clonality: Monoclonal
Clone: 24-31
Conjugation: R-PE
Epitope:
Host:
Isotype: Mouse IgG1
Reactivity: Human, Primate