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Specifications
- Antibody Type:Primary
- Antigen Symbol:CD272
- Clonality:Monoclonal
- Clone:ANC6E9
- ELISA:Yes
- Flow Cytometry:Yes
- Isotype:IgG1 kappa
- Reactivity:Human
- Size:120 tests
- Form:liquid
- Antigen Synonyms:B- and T-lymphocyte Attenuator|BTLA
- Storage Temperature:+4°C
- Shipping Temperature:-20° C
- Immunogen:Recombinant extracellular human CD272.
- Cat. No.:102512-758
- Supplier no.:ANC272040
Specifications
About this item
Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.
Type: Primary
Antigen: CD272
Clonality: Monoclonal
Clone: ANC6E9
Conjugation: FITC
Epitope:
Host:
Isotype: Mouse IgG1kappa
Reactivity: Human