Specifications
- Antibody Type:Primary
- Antigen Name:Cytochrome c oxidase subunit 7A-related protein, mitochondrial
- Antigen Symbol:COX7A2L
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:400 ul
- Epitope:Amino Acid Range = 37-65
- Form:Liquid
- Gene ID:O14548
- Antigen Synonyms:COX7A2L
- Modification:None
- Storage Buffer:Supplied in PBS with 0.09% (W/V) sodium azide.
- Molecular Weight:13 kDa
- Storage Temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0.5 mg/mL
- Shipping Temperature:4 °C
- Immunogen:This COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Cat. No.:76011-816
Specifications
About this item
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Type: Primary
Antigen: COX7A2L
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human, Mouse