- Antibody Type:Primary
- Antigen Name:Bone morphogenetic protein receptor type-1B
- Antigen Symbol:BMPR1B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human
- Western Blot:Yes
- Size:400 ul
- Epitope:Amino Acid Range = 134-162
- Form:Liquid
- Gene ID:O00238
- Antigen Synonyms:BMPR1B
- Modification:None
- Storage Buffer:Supplied in PBS with 0.09% (W/V) sodium azide.
- Molecular Weight:57 kDa
- Storage Temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0.5 mg/mL
- Shipping Temperature:4 °C
- Immunogen:This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human BMPR1B.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Cat. No.:76011-482
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Type: Primary
Antigen: BMPR1B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human