- Antibody Type:Primary
- Antigen Name:Cyclin-dependent kinase 8
- Antigen Symbol:CDK8
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Rabbit
- Reactivity:Human
- Western Blot:Yes
- Size:400 ul
- Epitope:Amino Acid Range = 249-277
- Form:Liquid
- Gene ID:P49336
- Antigen Synonyms:CDK8
- Modification:None
- Storage Buffer:Supplied in PBS with 0.09% (W/V) sodium azide.
- Molecular Weight:53 kDa
- Storage Temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:2 mg/mL
- Shipping Temperature:4 °C
- Immunogen:This CDK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human CDK8.
- Purification:This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Cat. No.:76011-404
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Type: Primary
Antigen: CDK8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human