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Anti-MLH1 Rabbit Polyclonal Antibody
Anti-MLH1 Rabbit Polyclonal Antibody
  76010-952
 :  Prosci
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Anti-MLH1 Rabbit Polyclonal Antibody
  76010-952
 :  Prosci
 :  55-988

 

  • Antibody Type:
    Primary
  • Antigen Name:
    DNA mismatch repair protein Mlh1
  • Antigen Symbol:
    MLH1
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Rabbit
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    400 ul
  • Epitope:
    Amino Acid Range = 452-480
  • Form:
    Liquid
  • Gene ID:
    P40692
  • Antigen Synonyms:
    MLH1
  • Modification:
    None
  • Storage Buffer:
    Supplied in PBS with 0.09% (W/V) sodium azide.
  • Molecular Weight:
    85 kDa
  • Storage Temperature:
    Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    0.4 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
  • Purification:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Cat. No.:
    76010-952

 

 

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50

Type: Primary
Antigen: MLH1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human