Specifications
- Antibody Type:Primary
- Antigen Name:Caspase recruitment domain-containing protein 16
- Antigen Symbol:CARD16
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Rabbit
- Reactivity:Human
- Western Blot:Yes
- Size:400 ul
- Epitope:Amino Acid Range = 37-65
- Form:Liquid
- Gene ID:Q5EG05
- Antigen Synonyms:CARD16
- Modification:None
- Storage Buffer:Supplied in PBS with 0.09% (W/V) sodium azide.
- Molecular Weight:23 kDa
- Storage Temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0.35 mg/mL
- Shipping Temperature:4 °C
- Immunogen:This COP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COP1.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Cat. No.:76010-220
Specifications
About this item
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
For FACS starting dilution is: 1:10~50 For WB starting dilution is: 1:1000
Type: Primary
Antigen: CARD16
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human