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Anti-CARD16 Rabbit Polyclonal Antibody
Anti-CARD16 Rabbit Polyclonal Antibody
Catalog # 76010-220
Supplier:  Prosci
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Anti-CARD16 Rabbit Polyclonal Antibody
Catalog # 76010-220
Supplier:  Prosci
Supplier Number:  55-786

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Caspase recruitment domain-containing protein 16
  • Antigen Symbol:
    CARD16
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Rabbit
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    400 ul
  • Epitope:
    Amino Acid Range = 37-65
  • Form:
    Liquid
  • Gene ID:
    Q5EG05
  • Antigen Synonyms:
    CARD16
  • Modification:
    None
  • Storage Buffer:
    Supplied in PBS with 0.09% (W/V) sodium azide.
  • Molecular Weight:
    23 kDa
  • Storage Temperature:
    Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    0.35 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    This COP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COP1.
  • Purification:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Cat. No.:
    76010-220

Specifications

About this item

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

For FACS starting dilution is: 1:10~50 For WB starting dilution is: 1:1000

Type: Primary
Antigen: CARD16
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human