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Anti-KMT2A Rabbit Polyclonal Antibody
Catalog # 76010-342
Supplier:  Prosci
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Anti-KMT2A Rabbit Polyclonal Antibody
Catalog # 76010-342
Supplier:  Prosci
Supplier Number:  55-727

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Histone-lysine N-methyltransferase 2A
  • Antigen Symbol:
    KMT2A
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Reactivity:
    Human
  • Size:
    400 ul
  • Epitope:
    Amino Acid Range = 3879-3908
  • Form:
    Liquid
  • Gene ID:
    Q03164
  • Antigen Synonyms:
    KMT2A
  • Modification:
    None
  • Storage Buffer:
    Supplied in PBS with 0.09% (W/V) sodium azide.
  • Molecular Weight:
    432 kDa
  • Storage Temperature:
    Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    2 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    This HRX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3879-3908 amino acids from the C-terminal region of human HRX.
  • Purification:
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
  • Cat. No.:
    76010-342

Specifications

About this item

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Tse et al. (1995) characterized 2 t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21, AF1Q, in 2 infants with acute myelomonocytic leukemia. In one of these patients, the derivative chromosome 11 represented an in-frame fusion of the N-terminal portion of the MLL gene to the complete AF1Q open reading frame, whereas the derivative chromosome 1 did not give rise to an open reading frame. This observation suggested that the N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23.

For FACS starting dilution is: 1:10~50 For IHC-P starting dilution is: 1:50~100

Type: Primary
Antigen: KMT2A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human