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Anti-PCDHGC3 Rabbit Polyclonal Antibody
Anti-PCDHGC3 Rabbit Polyclonal Antibody
Catalog # 76008-964
Supplier:  Prosci
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Anti-PCDHGC3 Rabbit Polyclonal Antibody
Catalog # 76008-964
Supplier:  Prosci
Supplier Number:  55-054

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Protocadherin gamma-C3
  • Antigen Symbol:
    PCDHGC3
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    400 ul
  • Epitope:
    Amino Acid Range = 511-539
  • Form:
    Liquid
  • Gene ID:
    Q9UN70
  • Antigen Synonyms:
    PCDHGC3
  • Modification:
    None
  • Storage Buffer:
    Supplied in PBS with 0.09% (W/V) sodium azide.
  • Molecular Weight:
    101 kDa
  • Storage Temperature:
    Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    0.5 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    This PCDHGC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the Central region of human PCDHGC3.
  • Purification:
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Cat. No.:
    76008-964

Specifications

About this item

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50

Type: Primary
Antigen: PCDHGC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human