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Specifications
- Antibody Type:Primary
- Antigen Name:CD107a
- Antigen Symbol:CD107a
- Clonality:Monoclonal
- Clone:1D4B
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow Cytometry:Yes
- Host:Rat
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG2a
- Reactivity:Mouse
- Western Blot:Yes
- Size:0.5 mg
- Form:Liquid
- Gene ID:16783
- Antigen Synonyms:lysosomal-associated membrane protein 1|LAMP-1
- Storage Buffer:Supplied in PBS/NaN3
- Storage Temperature:2-8°C
- Concentration:0.5 mg/mL
- Shipping Temperature:Ambient Temperature
- Immunogen:Plasma membrane fraction of mouse embryo NIH/3T3 cell line
- Cat. No.:100244-162
- Supplier no.:1920-02
Specifications
About this item
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.
Type: Primary
Antigen: CD107a
Clonality: Monoclonal
Clone: 1D4B
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse