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Specifications
- Antibody Type:Primary
- Antigen Name:CD19
- Antigen Symbol:CD19
- Clonality:Monoclonal
- Clone:6D5
- Conjugation:RPE (R-Phycoerythrin)/Cy7®
- Flow Cytometry:Yes
- Host:Rat
- Isotype:IgG2a
- Reactivity:Mouse
- Size:0.1 mg
- Form:Liquid
- Gene ID:12478
- Antigen Synonyms:Leu-12|B4
- Storage Buffer:Supplied in PBS/NaN3 and a stabilizing agent
- Storage Temperature:2-8°C
- Concentration:0.1 mg/mL
- Shipping Temperature:Ambient Temperature
- Immunogen:Mouse CD19-expressing K562 human erythroleukemia cells
- Cat. No.:100243-280
- Supplier no.:1575-17
Specifications
About this item
CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.
Type: Primary
Antigen: CD19
Clonality: Monoclonal
Clone: 6D5
Conjugation: RPE (R-Phycoerythrin)/Cy7®
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse