RNase H is an endonuclease that specifically hydrolyzes the phosphodiester bonds of RNA hybridized to DNA.

• For sequencing, cDNA synthesis and cDNA cloning
• Endonuclease that Specifically Hydrolyzes the Phosphodiester Bonds of RNA Hybridized to DNA
• Removes the RNA strand prior to second-strand cDNA synthesis
• Analyzes in vitro polyadenylation reaction products
• Supplied at a concentration of 0.5-2u/microl

Ribonuclease H (RNase H) is an endonuclease that specifically hydrolyzes the phosphodiester bonds of RNA hybridized to DNA to produce 3'-OH and 5'-P-terminated products. It will not degrade single-stranded nucleic acids, double-stranded DNA or double-stranded RNA.