About this item
Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.
- High quality
- Low endotoxin
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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Mouse
- Storage Conditions:–20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤1
- Biological Activity:Bioactivity Assay: Ability to induce bioluminescence in engineered RANKL bioassay cells, ED₅₀ ≤50 ng/ml, Bioactivity ≥2.0×10⁴ units/mg
- Gene ID:O35235
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:OPGL|TNFSF11|ODF|TRANCE
- Protein/Peptide Name:Rank ligand (AF)
- Purity:≥95%
- Molecular Weight:19.5 kDa
- Sequence:MPAMMEGSWLD VAQRGKPEAQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID
- Endotoxin Level:Low
- Formulation:10 mM Sodium phosphate and 20 mM Sodium chloride, pH 7.5
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay
Specifications
Related Information
Literature reference - PubMed ID 22807064 Literature reference - PubMed ID 25914241
Additional Product Details
Shenandoah_Biotechnology_Product_Catalog