LeukoPaks are collected in FDA-regulated collection centers from IRB consented volunteer donors.
- Collected in a regulated environment
- FDA-registered donor center
- >85% of TNC are MNCs
A leukopak is an enriched leukapheresis product collected from normal peripheral blood
Leukopaks from mobilized peripheral blood are collected from healthy human volunteer donors under IRB approved informed consent by leukapheresis using the COBE® Spectra or Spectra Optia® Apheresis System MNC collection protocol. Donors are injected with G-CSF (Neupogen® - FDA approved), which stimulates the bone marrow to produce a large number of hematopoietic and progenitor stem cells and mobilizes them into the peripheral blood stream. Mozobil® in combination with G-CSF is also available. This mononuclear cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.
It is composed of a variety of blood cells including monocytes, lymphocytes, platelets, plasma, and red cells. A leukopak contains a higher concentration of cells as compared to standard venipuncture collection methods or buffy coat products.
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