About this item
Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7,) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells.
- Animal-free
Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Specifications
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:Store at –20 °C prior to opening
- Endotoxin Content:≤1.00 EUs/μg
- Biological Activity:OCI-AML5 cell proliferation at less than or equal to 10 ng/mL or (1 x 10^5 units/mg specific units)
- Reconstitution Instructions:Reconstitute with Sterile water at 0.1 mg/mL
- Protease-free:Y
- Animal-Free:Y
- Protein Synonyms:Fms-related tyrosine kinase 3 ligand|FLt3L
- Protein/Peptide Name:FLT-3 Ligand
- Purity:>95%
- Molecular Weight:17.6 (kDa) Monomer
- Sequence:MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
- Endotoxin Level:Low
- Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5
- Shipping Temperature:Ambient
- Conjugation:Unconjugated
- Gene ID:P49771
- Endotoxin-free:N
- Carrier-Free:Y
- Nuclease-free:N
- Grade:RUO
- Tested Applications:Bioassay
Specifications
Related Information
Literature reference - PubMed ID 28211886 Literature reference - PubMed ID 29520027
Additional Product Details
Shenandoah_Biotechnology_Product_Catalog