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Mouse Recombinant IL-2 non-lytic (from NS1 Cells)
Mouse Recombinant IL-2 non-lytic (from NS1 Cells)
Catalog # 75794-482
Supplier:  Prosci
CAS Number:  
Mouse Recombinant IL-2 non-lytic (from NS1 Cells)
Catalog # 75794-482
Supplier:  Prosci
Supplier Number:  90-468
CAS Number:  

Specifications

  • Protein/Peptide Type:
    Recombinant
  • Source:
    NS1 cells
  • Species:
    Mouse
  • Size:
    10 μg
  • Tag sequence:
    Fc Tag
  • Storage Conditions:
    Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
  • Biological Activity:
    Specific Activity: 1-1.5 x106 Units/mg, measured using CTLL indicator cells.
    Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic autoimmunity in nonobese diabetic mice.
  • Protein Synonyms:
    Interleukin-2|Aldesleukin
  • Protein/Peptide Name:
    IL-2 non-lytic
  • Purity:
    >98% (SDS-PAGE)
  • Sequence:
    21-169
  • Formulation:
    Lyophilized from 0.2um-filtered solution in PBS.
  • Cat. No.:
    75794-482
  • Supplier no.:
    90-468

Specifications

About this item

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.

  • Fusion-Tag: Fc Tag

This recombinant proteins is for research use only.