Mouse Recombinant IL-2 non-lytic (from NS1 Cells)
Catalog # 75794-482
Supplier: Prosci
CAS Number:
Specifications
- Protein/Peptide Type:Recombinant
- Source:NS1 cells
- Species:Mouse
- Size:10 μg
- Tag sequence:Fc Tag
- Storage Conditions:Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
- Biological Activity:Specific Activity: 1-1.5 x106 Units/mg, measured using CTLL indicator cells.
Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic autoimmunity in nonobese diabetic mice. - Protein Synonyms:Interleukin-2|Aldesleukin
- Protein/Peptide Name:IL-2 non-lytic
- Purity:>98% (SDS-PAGE)
- Sequence:21-169
- Formulation:Lyophilized from 0.2um-filtered solution in PBS.
- Cat. No.:75794-482
- Supplier no.:90-468
Specifications
About this item
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
- Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.