Specifications

Protein/Peptide Type:
Recombinant
Source:
HEK293 cells
Species:
Human
Size:
10 μg
Tag sequence:
DDDDK Tag
Storage Conditions:
Stable for at least 6 months after receipt when stored at −20 °C.
Protein Synonyms:
ANGPT2|ANG2|Angiopoietin-2|AGPT2
Protein/Peptide Name:
Angiopoietin 2
Purity:
>95% (SDS-PAGE)
Sequence:
19-496
Formulation:
Lyophilized, Contains PBS with trehalose and Brij35.
Cat. No.:
75793-824
Supplier no.:
90-311

Specifications

About this item

Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.

Fusion-Tag: DDDDK Tag

This recombinant proteins is for research use only.