Advanced
Order Entry
Puerto Rico
ContactUsLinkComponent
Human Recombinant beta-1,3-Glucuronyltransferase 3 (from E. coli)
Human Recombinant beta-1,3-Glucuronyltransferase 3 (from E. coli)
Catalog # 75791-574
Supplier:  Prosci
CAS Number:  
Human Recombinant beta-1,3-Glucuronyltransferase 3 (from E. coli)
Catalog # 75791-574
Supplier:  Prosci
Supplier Number:  92-502
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage Conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme Name:
    beta-1,3-Glucuronyltransferase 3
  • Enzyme Synonyms:
    B3GAT3, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, Beta-1, 3-glucuronyltransferase 3, Glucuronosyltransferase I, GlcAT-I, GlcUAT-I, Gal beta-1, 3-Gal-R glucuronyltransferase, REF: C1005
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    30.4 kD
  • Sequence:
    Glu72-Val335
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris, 150 mM NaC,2 mM EDTA, 20% glycerol,pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Cat. No.:
    75791-574
  • Supplier no.:
    92-502

Specifications

About this item

Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3) is an enzyme that in humans is encoded by the B3GAT3 gene, belongs to the glycosyltransferase 43 family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

B3GAT3 is involved in a number of biological processes such as catalyzing the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans, forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate, gGlycosaminoglycans biosynthesis, transfering a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans.It also plays a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins , hows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc and stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.