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- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage Conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein Synonyms:FIS1|TTC11|FIS1 Homolog|Mitochondrial Fission 1 Protein|hFis1|Tetratricopeptide Repeat Protein 11|TPR Repeat Protein 11|CGI-135
- Protein/Peptide Name:Mitochondrial Fission 1
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular Weight:15.2 kD
- Sequence:Met1-Gly122
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM Tris, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:Bioassay
- Cat. No.:75790-762
- Supplier no.:92-084
Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.