Order Entry
Puerto Rico
ContactUsLinkComponent
Human Recombinant IGF2 mRNA-Binding 2 (from E. coli)
Human Recombinant IGF2 mRNA-Binding 2 (from E. coli)
Catalog # 75790-708
Supplier:  Prosci
CAS Number:  
Human Recombinant IGF2 mRNA-Binding 2 (from E. coli)
Catalog # 75790-708
Supplier:  Prosci
Supplier Number:  92-057
CAS Number:  

Specifications

  • Protein/Peptide Type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His, N-T7 tag
  • Storage Conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein Synonyms:
    VICKZ Family Member 2|IGF2BP2|VICKZ2|IMP2|IMP-2|IGF-II mRNA-Binding Protein 2|IGF2 mRNA-Binding Protein 2|Hepatocellular Carcinoma Autoantigen p62|Insulin-like Growth Factor 2 mRNA-Binding Protein 2
  • Protein/Peptide Name:
    IGF2 mRNA-Binding 2
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    27.2 kD
  • Sequence:
    Met1-Thr220
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    Bioassay
  • Cat. No.:
    75790-708
  • Supplier no.:
    92-057

Specifications

About this item

Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

  • Fusion-Tag: C-6 His, N-T7 tag

This recombinant protein can be used for biological assays. For research use only.