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Human Recombinant Inositol Monophosphatase 2 (from E. coli)
Human Recombinant Inositol Monophosphatase 2 (from E. coli)
Catalog # 75788-654
Supplier:  Prosci
CAS Number:  
Human Recombinant Inositol Monophosphatase 2 (from E. coli)
Catalog # 75788-654
Supplier:  Prosci
Supplier Number:  91-990
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    N-6 His tag
  • Storage Conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme Name:
    Inositol Monophosphatase 2
  • Enzyme Synonyms:
    Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    33.5 kD
  • Sequence:
    Met1-Lys288
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris, 2 mM DTT, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    Bioassay
  • Cat. No.:
    75788-654
  • Supplier no.:
    91-990

Specifications

About this item

Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: N-6 His tag

IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.