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Specifications
- Enzyme type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage Conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Enzyme Name:GMP Reductase 1
- Enzyme Synonyms:GMP Reductase 1, Guanosine 5'-Monophosphate Oxidoreductase 1, Guanosine Monophosphate Reductase 1, GMPR, GMPR1
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular Weight:38.5 kD
- Sequence:Met1-Ser345
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM Tris-HCl, 40% glycerol, 0.15 M NaCl and 1 mM DTT, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:Bioassay
- Cat. No.:75789-992
- Supplier no.:91-666
Specifications
About this item
GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag
GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.