Human Recombinant Carbonic Anhydrase 8 (from E. coli)

75788-914

: Prosci

Human Recombinant Carbonic Anhydrase 8 (from E. coli)

75788-914

: Prosci

: 91-095

Enzyme type:
Recombinant
Source:
E. coli
Species:
Human
Size:
0.05 mg
Tag sequence:
C-6 His tag
Storage Conditions:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
Endotoxin Content:
<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Enzyme Name:
Carbonic Anhydrase 8
Enzyme Synonyms:
Carbonic Anhydrase-Related Protein, CARP, Carbonic Anhydrase VIII, CA-VIII, CA8, CALS
Purity:
>95% as determined by reducing SDS-PAGE
Molecular Weight:
34.04 kD
Sequence:
Ala2-Gln290
Formulation:
Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 500 mM NaCl, 1 mM DTT, pH 8.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested Applications:
Bioassay
Cat. No.:
75788-914
Supplier no.:
91-095

Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.