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Specifications
- Antibody Type:Primary
- Antigen Name:activin receptor IIB
- Antigen Symbol:Acvr2b
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:50 ug
- Environmentally Preferable:
- Form:Liquid
- Gene ID:P27040
- Antigen Synonyms:Acvr2b
- Storage Buffer:Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide.
- Storage Temperature:Stable for at least 1 year after receipt when stored at –20 °C.
- Concentration:500 ug/mL
- Shipping Temperature:4 °C
- Immunogen:Recombinant extracellular domain (ecd) of mouse activin receptor IIB.
- Purification:Antigen affinity purified.
- Cat. No.:75793-498
- Supplier no.:36-351
Specifications
About this item
Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.
ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application.
Type: Primary
Antigen: Acvr2b
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse