Specifications
- Antibody Type:Primary
- Antigen Name:Activating Transcription Factor 4
- Antigen Symbol:ATF4
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Form:Liquid
- Gene ID:468
- Antigen Synonyms:DNA-binding protein TAXREB67|cAMP-dependent transcription factor ATF-4|Cyclic AMP-dependent transcription factor ATF-4|TXREB|TaxREB67|Tax-responsive enhancer element-binding protein 67|CREB2|Activating transcription factor 4|cAMP-responsive element-binding protein 2|CREB-2|Cyclic AMP-responsive element-binding protein 2|ATF4
- Modification:phospho-Ser219
- Storage Buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular Weight:38 kDa
- Storage Temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/ml
- Shipping Temperature:–20 °C
- Immunogen:ATF-4 (phospho Ser219) antibody was raised against a peptide sequence around phosphorylation site of Serine 219 (N-D-S (p)-G-T) derived from Human ATF-4.
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. No.:10814-084
- Supplier no.:79-940
Specifications
About this item
ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding
protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Western Blot: 1:500 - 1:1000
Type: Primary
Antigen: ATF4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse