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Anti-ATF4 Rabbit Polyclonal Antibody
Anti-ATF4 Rabbit Polyclonal Antibody
Catalog # 10814-084
Supplier:  Prosci
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Anti-ATF4 Rabbit Polyclonal Antibody
Catalog # 10814-084
Supplier:  Prosci
Supplier Number:  79-940

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Activating Transcription Factor 4
  • Antigen Symbol:
    ATF4
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Mouse
  • Western Blot:
    Yes
  • Size:
    0.1 mg
  • Form:
    Liquid
  • Gene ID:
    468
  • Antigen Synonyms:
    DNA-binding protein TAXREB67|cAMP-dependent transcription factor ATF-4|Cyclic AMP-dependent transcription factor ATF-4|TXREB|TaxREB67|Tax-responsive enhancer element-binding protein 67|CREB2|Activating transcription factor 4|cAMP-responsive element-binding protein 2|CREB-2|Cyclic AMP-responsive element-binding protein 2|ATF4
  • Modification:
    phospho-Ser219
  • Storage Buffer:
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Molecular Weight:
    38 kDa
  • Storage Temperature:
    Store antibody at –20 °C for up to one year.
  • Concentration:
    1 mg/ml
  • Shipping Temperature:
    –20 °C
  • Immunogen:
    ATF-4 (phospho Ser219) antibody was raised against a peptide sequence around phosphorylation site of Serine 219 (N-D-S (p)-G-T) derived from Human ATF-4.
  • Purification:
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Cat. No.:
    10814-084
  • Supplier no.:
    79-940

Specifications

About this item

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding
protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Western Blot: 1:500 - 1:1000

Type: Primary
Antigen: ATF4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse