Specifications
- Antibody Type:Primary
- Antigen Name:fibroblast growth factor receptor 1, fibroblast growth factor receptor 2
- Antigen Symbol:FGFR1, FGFR2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Form:Liquid
- Gene ID:P11362/P21802
- Antigen Synonyms:FGFR1, FGFR2
- Modification:Tyr 463/466
- Storage Buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular Weight:91 kDa
- Storage Temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. No.:10813-764
- Supplier no.:79-883
Specifications
About this item
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Type: Primary
Antigen: FGFR1, FGFR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse