Anti-TOP2A Rabbit Polyclonal Antibody
Catalog # 10813-746
Supplier: Prosci
Specifications
- Antibody Type:Primary
- Antigen Name:topoisomerase (DNA) II alpha 170kDa
- Antigen Symbol:TOP2A
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:0.1 mg
- Form:Liquid
- Gene ID:P11388
- Antigen Synonyms:TOP2A
- Modification:Thr 1343
- Storage Buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular Weight:190 kDa
- Storage Temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:TOP2A (phospho Thr1343) antibody was raised against a peptide sequence around phosphorylation site of threonine1343 (E-K-T (p)-D-D) derived from Human TOP2A.
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. No.:10813-746
- Supplier no.:79-874
Specifications
About this item
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.
Western Blot: 1:500~1:1000
Type: Primary
Antigen: TOP2A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human