Human Recombinant Pleiotrophin (from E. coli)

About this item

Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis, and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas. Recombinant Human Pleiotrophin is a 15.4 kDa protein containing 136 amino acid residues and five intra-molecular disulfide bonds.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
5764 P21246
Reconstitution Instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein Synonyms:
Heparin Affin Regulatory Protein (HARP)|Heparin-Binding Growth Factor-8 (HBGF-8)|Osteoblast-Specific Factor 1 (OSF-1)|PTN
Protein/Peptide Name:
Pleiotrophin
Purity:
0.98
Molecular Weight:
15.4 kDa
Sequence:
GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
Endotoxin Level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping Temperature:
Ambient