Rat Recombinant IL-1 Alpha (from E. coli)

About this item

IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Rat IL-1α is a 17.7 kDa protein containing 155 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Rat
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
24493 P16598
Reconstitution Instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein Synonyms:
Hematopoietin-1|Lymphocyte-Activating Factor (LAF)|Endogenous Pyrogen (EP)|Mononuclear Cell Factor (MCF)|Interleukin-1α|Leukocyte Endogenous Mediator (LEM)
Protein/Peptide Name:
IL-1alpha
Purity:
0.98
Molecular Weight:
17.7 kDa
Sequence:
MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
Endotoxin Level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping Temperature:
Ambient