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Human Recombinant sCD14 (from HEK293 Cells)
Human Recombinant sCD14 (from HEK293 Cells)
Catalog # 10779-062
Supplier:  Peprotech
CAS Number:  
Human Recombinant sCD14 (from HEK293 Cells)
Catalog # 10779-062
Supplier:  Peprotech
Supplier Number:  110-01-10UG
CAS Number:  

Specifications

  • Conjugation:
    Unconjugated
  • Protein Function:
    Cytokines and Growth Factors
  • Protein/Peptide Type:
    Recombinant
  • Source:
    HEK293 cells
  • Species:
    Human
  • Size:
    10 μg
  • Storage Conditions:
    Store at –20 °C prior to reconstitution.
  • Endotoxin Content:
    >0.1 ng/μg
  • Biological Activity:
    Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Form:
    Lyophilized
  • Gene ID:
    929 P08571
  • Reconstitution Instructions:
    Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Protease-free:
    Y
  • Protein Synonyms:
    soluble CD14|Monocyte differentiation antigen CD14
  • Protein/Peptide Name:
    sCD14
  • Purity:
    0.95
  • Molecular Weight:
    35.6 kDa
  • Sequence:
    TTPEPCELDD EDFRCVCNFS EPQPDWSEAF QCVSAVEVEI HAGGLNLEPF LKRVDADADP RQYADTVKAL RVRRLTVGAA QVPAQLLVGA LRVLAYSRLK ELTLEDLKIT GTMPPLPLEA TGLALSSLRL RNVSWATGRS WLAELQQWLK PGLKVLSIAQ AHSPAFSCEQ VRAFPALTSL DLSDNPGLGE RGLMAALCPH KFPAIQNLAL RNTGMETPTG VCAALAAAGV QPHSLDLSHN SLRATVNPSA PRCMWSSALN SLNLSFAGLE QVPKGLPAKL RVLDLSCNRL NRAPQPDELP EVDNLTLDGN PFLVPGTALP HEGSMNSGVV P
  • Endotoxin Level:
    Low
  • Formulation:
    Formulation can vary. Please refer to product CoA for information.
  • Shipping Temperature:
    Ambient
  • Cat. No.:
    10779-062
  • Origin:
    US
  • Supplier no.:
    110-01-10UG

Specifications

About this item

CD14 is a cell surface-anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-κB. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant Human sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor. The calculated molecular weight of Recombinant Human sCD14 is 35.6 kDa.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.