IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. Manufactured using all Animal-Free reagents.
- Carrier free
- Animal-free
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:−20 °C
- Endotoxin Content:<0.1 ng/μg of protein (<1 EU/μg).
- Biological Activity:The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
- Animal-Free:Y
- Protein/Peptide Name:IL2
- Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Formulation:Lyophilized
- Shipping Temperature:RT