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Human Recombinant BMP2 (from E. coli)

Supplier:   Peprotech
Human Recombinant BMP2 (from <i>E. coli</i>)
Supplier:  Peprotech
Certificates

7 Options Available Below

  • Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
  • Return Policy
Product Details & Documents

BMPs (Bone Morphogenetic Proteins) belong to the TGF-β superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis, and is expressed in a variety of tissues, including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human BMP-2 is a 26.0 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains. Manufactured using all Animal-Free reagents.

  • Carrier free
  • Animal-free

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

 : For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications for Product Family

Specifications

Specifications

  • Catalog No:
  • 10778-144
  • 10778-146
  • 10778-148
  • 10778-150
  • 10778-152
  • 10778-154
  • 10778-156
  • Protein/Peptide Name:
  • BMP2
  • BMP2
  • BMP2
  • BMP2
  • BMP2
  • BMP2
  • BMP2
  • Protein/Peptide Type:
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Species:
  • Human
  • Human
  • Human
  • Human
  • Human
  • Human
  • Human
  • Source:
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • Animal-Free:
  • Y
  • Y
  • Y
  • Y
  • Y
  • Y
  • Y
  • Endotoxin Content:
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • <0.1 ng/μg of protein (<1 EU/μg).
  • Biological Activity:
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
  • Purity:
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Formulation:
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Storage Conditions:
  • −20 °C
  • −20 °C
  • −20 °C
  • −20 °C
  • −20 °C
  • −20 °C
  • −20 °C
  • Shipping Temperature:
  • RT
  • RT
  • RT
  • RT
  • RT
  • RT
  • RT

Specifications

Product Family Options

Product Information

  • Size
    Origin
    Availability
    Price
  • 10778-144
    2 µg
    US
    Log in for availability
    Log in for availability
    Each (2µG)
    Each (2µG) - $197.80
    $197.80
    Each (2µG)
       $197.80
     
    Supplier Number: AF-120-02-2UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-144
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-146
    10 µg
    US
    Log in for availability
    Log in for availability
    Each (10µG)
    Each (10µG) - $462.32
    $462.32
    Each (10µG)
       $462.32
     
    Supplier Number: AF-120-02-10UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-146
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-148
    50 µg
    US
    Log in for availability
    Log in for availability
    Each (50µG)
    Each (50µG) - $1,105.50
    $1,105.50
    Each (50µG)
       $1,105.50
     
    Supplier Number: AF-120-02-50UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-148
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-150
    100 µg
    US
    Log in for availability
    Log in for availability
    Each (100µG)
    Each (100µG) - $1,785.26
    $1,785.26
    Each (100µG)
       $1,785.26
     
    Supplier Number: AF-120-02-100UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-150
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-152
    250 µg
    US
    Log in for availability
    Log in for availability
    Each (250µG)
    Each (250µG) - $2,924.88
    $2,924.88
    Each (250µG)
       $2,924.88
     
    Supplier Number: AF-120-02-250UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-152
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-154
    500 µg
    US
    Log in for availability
    Log in for availability
    Each (500µG)
    Each (500µG) - $4,540.50
    $4,540.50
    Each (500µG)
       $4,540.50
     
    Supplier Number: AF-120-02-500UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-154
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
  • 10778-156
    1 mg
    US
    Log in for availability
    Log in for availability
    Each (1mg)
    Each (1mg) - $7,540.48
    $7,540.48
    Each (1mg)
       $7,540.48
     
    Supplier Number: AF-120-02-1MG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-156
    Protein/Peptide Name
    BMP2
    Protein/Peptide Type
    Recombinant
    Species
    Human
    Source
    E. coli
    Animal-Free
    Y
    Endotoxin Content
    <0.1 ng/μg of protein (<1 EU/μg).
    Biological Activity
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
    Purity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.
    Formulation
    Lyophilized
    Storage Conditions
    −20 °C
    Shipping Temperature
    RT
   
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