Human Recombinant IL-16 (from E. coli)
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils.
- IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells
- Human and murine IL-16 show significant cross-species reactivity
- Recombinant Human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues
Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity.
: For research use only. Not for use in diagnostic or therapeutic procedures.
- Conjugation:Unconjugated
- Protein Function:Cytokines and Growth Factors
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:Store at –20 °C prior to reconstitution.
- Endotoxin Content:>0.1 ng/μg
- Biological Activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Form:Lyophilized
- Gene ID:3603 Q14005
- Reconstitution Instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Protease-free:Y
- Protein Synonyms:Interleukin-16|LCF (Lymphocyte Chemoattractant Factor)
- Protein/Peptide Name:IL-16
- Purity:0.98
- Molecular Weight:13.3 kDa
- Sequence:PDLNSSTDSA ASASAASDVS VESTAEATVC TVTLEKMSAG LGFSLEGGKG SLHGDKPLTI NRIFKGAASE QSETVQPGDE ILQLGGTAMQ GLTRFEAWNI IKALPDGPVT IVIRRKSLQS KETTAAGDS
- Endotoxin Level:Low
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Shipping Temperature:Ambient