Human Recombinant IL-16 (from E. coli)

About this item

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils.

IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells
Human and murine IL-16 show significant cross-species reactivity
Recombinant Human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues

Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity.

Caution: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
3603 Q14005
Reconstitution Instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein Synonyms:
Interleukin-16|LCF (Lymphocyte Chemoattractant Factor)
Protein/Peptide Name:
IL-16
Purity:
0.98
Molecular Weight:
13.3 kDa
Sequence:
PDLNSSTDSA ASASAASDVS VESTAEATVC TVTLEKMSAG LGFSLEGGKG SLHGDKPLTI NRIFKGAASE QSETVQPGDE ILQLGGTAMQ GLTRFEAWNI IKALPDGPVT IVIRRKSLQS KETTAAGDS
Endotoxin Level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping Temperature:
Ambient