About this item
GDF-2 belongs to the TGF-β cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a 24.1 kDa disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.
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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokines and Growth Factors
- Protein/Peptide Type:Recombinant
- Source:CHO cells
- Species:Human
- Storage Conditions:Store at –20 °C prior to reconstitution.
- Endotoxin Content:>0.1 ng/μg
- Biological Activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Form:Lyophilized
- Gene ID:2658 Q9UK05
- Reconstitution Instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Protease-free:Y
- Protein Synonyms:Growth/Differentiation Factor-2|BMP-9
- Protein/Peptide Name:GDF-2
- Purity:0.95
- Molecular Weight:24.1 kDa
- Sequence:SAGAGSHCQK TSLRVNFEDI GWDSWIIAPK EYEAYECKGG CFFPLADDVT PTKHAIVQTL VHLKFPTKVG KACCVPTKLS PISVLYKDDM GVPTLKYHYE GMSVAECGCR
- Endotoxin Level:Low
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Shipping Temperature:Ambient