Human Recombinant Amphiregulin (from E. coli)

About this item

Amphiregulin is an EGF-related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Human Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
374 P15514
Reconstitution Instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein Synonyms:
Colorectum cell-Derived Growth Factor (CRDGF)|AR|AREG
Protein/Peptide Name:
Amphiregulin
Purity:
0.95
Molecular Weight:
11.3 kDa
Sequence:
SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK
Endotoxin Level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping Temperature:
Ambient