Human Recombinant IGF-II (from E. coli)

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

Produced from genetically modified E. coli
Contains 134 amino acids

These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only. Not for use in diagnostic or therapeutic procedures.

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
CTLL-2 cell proliferation at ≤3 ng/ml (or ≥3.3×10⁵ units/mg specific units)
International Units = 1.8×10⁴ IU/µg
Form:
Lyophilized
Gene ID:
3481 P01344
Reconstitution Instructions:
Reconstitute with sterile 10 mM HCl at 0.1 mg/ml
Protease-free:
Y
Protein Synonyms:
Aldesleukin|TCGF|T cell growth factor
UniProtKB:
P60568
Protein/Peptide Name:
IL-2
Purity:
>95%
Molecular Weight:
15.5 kDa (monomer)
Sequence:
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
Endotoxin Level:
≤1 EUs/μg
Formulation:
Lyophilised from a sterile (0.2 µm) filtered aqueous solution containing 0.1% trifluoroacetic acid (TFA)
Shipping Temperature:
Ambient