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Anti-JMJD2A Rabbit Polyclonal Antibody
Anti-JMJD2A Rabbit Polyclonal Antibody
Catalog # 10475-548
Supplier:  Bioss
Anti-JMJD2A Rabbit Polyclonal Antibody
Catalog # 10475-548
Supplier:  Bioss
Supplier Number:  BS-8046R

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Jumonji Domain Containing protein 2A
  • Antigen Symbol:
    JMJD2A
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    100 µg
  • Cross Adsorption:
    No
  • Form:
    liquid
  • Antigen Synonyms:
    JmjC domain containing histone demethylation protein 3A|KDM4A|JmjC domain-containing histone demethylation protein 3A|Jumonji domain containing 2A|JMJD2|JMJ2A|Jumonji domain-containing protein 2A|KDM2A_HUMAN|jumonji C domain containing histone demethylase 3A|KIAA0677|Jumonji domain containing protein 2A|Lysine-specic demethylase 4A.|Jumonji domain containing 2
  • Storage Buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
  • Storage Temperature:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping Temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Cat. No.:
    10475-548
  • Supplier no.:
    BS-8046R

Specifications

About this item

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: JMJD2A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat