Specifications
- Antibody Type:Primary
- Antigen Name:5' AMP-activated protein kinase beta 1 And 2
- Antigen Symbol:AMPK beta 1 + 2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Cross Adsorption:No
- Form:liquid
- Gene ID:5565, 5564
- Antigen Synonyms:Protein kinase AMP activated beta 2 non catalytic subunit|PRKAB 2|AMPK subunit beta-1|AMPK beta 2 chain|AMPK beta 2|AMP activated protein kinase beta 2 non catalytic subunit|PRKAB1|AMPKb
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage Temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Immunogen:220-270/272
- Purification:Purified by Protein A
- Cat. No.:10390-858
- Supplier no.:BS-3967R
Specifications
About this item
PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: AMPK beta 1 + 2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat