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Anti-GBA3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Anti-GBA3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Catalog # 10295-474
Supplier:  Bioss
Anti-GBA3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Catalog # 10295-474
Supplier:  Bioss
Supplier Number:  BS-13298R-FITC

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Glucosidase, Beta, Acid 3 (Gene/Pseudogene)
  • Antigen Symbol:
    GBA3
  • Clonality:
    Polyclonal
  • Conjugation:
    FITC (Fluorescein Isothiocyanate)
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat
  • Size:
    100 µL
  • Cross Adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    57733
  • Antigen Synonyms:
    CBGL1|KLRP|GLUC|CBG
  • Storage Buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Storage Temperature:
    Store at 4°C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping Temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Cat. No.:
    10295-474
  • Supplier no.:
    BS-13298R-FITC

Specifications

About this item

CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GBA3/CBG
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat